WEE1 and PARP-1 play critical roles in myelodysplastic syndrome and acute myeloid leukemia treatment

BACKGROUND: Myelodysplastic syndrome (MDS) is a clonal bone marrow disorder defined by cytopenia and is associated with an increased risk of transformation to acute myeloid leukemia (AML). The outcome of MDS is poor, so alternative therapeutic approaches are needed to improve survival. The inhibitio...

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Detalles Bibliográficos
Autores principales: Okabe, Seiichi, Tanaka, Yuko, Moriyama, Mitsuru, Gotoh, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304360/
https://www.ncbi.nlm.nih.gov/pubmed/37370065
http://dx.doi.org/10.1186/s12935-023-02961-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304360/
https://www.ncbi.nlm.nih.gov/pubmed/37370065
http://dx.doi.org/10.1186/s12935-023-02961-3

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