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Discrete Element Method Evaluation of Triboelectric Charging Due to Powder Handling in the Capsule of a DPI

The generation and accumulation of an electrostatic charge from handling pharmaceutical powders is a well-known phenomenon, given the insulating nature of most APIs (Active Pharmaceutical Ingredients) and excipients. In capsule-based DPIs (Dry Powder Inhalers), the formulation is stored in a gelatin...

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Detalles Bibliográficos
Autores principales: Alfano, Francesca Orsola, Di Renzo, Alberto, Di Maio, Francesco Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304489/
https://www.ncbi.nlm.nih.gov/pubmed/37376210
http://dx.doi.org/10.3390/pharmaceutics15061762