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Discrete Element Method Evaluation of Triboelectric Charging Due to Powder Handling in the Capsule of a DPI
The generation and accumulation of an electrostatic charge from handling pharmaceutical powders is a well-known phenomenon, given the insulating nature of most APIs (Active Pharmaceutical Ingredients) and excipients. In capsule-based DPIs (Dry Powder Inhalers), the formulation is stored in a gelatin...
Autores principales: | Alfano, Francesca Orsola, Di Renzo, Alberto, Di Maio, Francesco Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304489/ https://www.ncbi.nlm.nih.gov/pubmed/37376210 http://dx.doi.org/10.3390/pharmaceutics15061762 |
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