Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells

Combretastatin derivatives is a promising class of antitumor agents, tubulin assembly inhibitors. However, due to poor solubility and insufficient selectivity to tumor cells, we believe, their therapeutic potential has not been fully realized yet. This paper describes polymeric micelles based on chi...

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Detalles Bibliográficos
Autores principales: Zlotnikov, Igor D., Ezhov, Alexander A., Ferberg, Artem S., Krylov, Sergey S., Semenova, Marina N., Semenov, Victor V., Kudryashova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304518/
https://www.ncbi.nlm.nih.gov/pubmed/37376064
http://dx.doi.org/10.3390/pharmaceutics15061613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304518/
https://www.ncbi.nlm.nih.gov/pubmed/37376064
http://dx.doi.org/10.3390/pharmaceutics15061613

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