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Gut Microbiota-Mediated Pharmacokinetic Drug–Drug Interactions between Mycophenolic Acid and Trimethoprim-Sulfamethoxazole in Humans

Mycophenolic acid (MPA) and trimethoprim-sulfamethoxazole (TMP-SMX) are commonly prescribed together in certain groups of patients, including solid organ transplant recipients. However, little is known about the pharmacokinetic drug–drug interactions (DDIs) between these two medications. Therefore,...

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Detalles Bibliográficos
Autores principales: Dukaew, Nahathai, Thongkumkoon, Patcharawadee, Sirikaew, Nutnicha, Dissook, Sivamoke, Sakuludomkan, Wannachai, Tongjai, Siripong, Thiennimitr, Parameth, Na Takuathung, Mingkwan, Benjanuwattra, Juthipong, Kongthaweelert, Prachya, Koonrungsesomboon, Nut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304707/
https://www.ncbi.nlm.nih.gov/pubmed/37376182
http://dx.doi.org/10.3390/pharmaceutics15061734