Downregulation of connexin 43-based gap junctions underlies propofol-induced excessive relaxation in hypertensive vascular smooth muscle cells

BACKGROUND: Postinduction hypotension caused by propofol remains a non-negligible problem for anesthesiologists, and is especially severe in chronic hypertensive patients with long-term vasoconstriction and decreased vascular elasticity. The functional change in gap junctions composed of Cx43 (Cx43-...

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Detalles Bibliográficos
Autores principales: Zeng, Weiqi, Deng, Zhizhao, Gao, Yingxin, Sun, Guoliang, Li, Xianlong, Yuan, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304740/
https://www.ncbi.nlm.nih.gov/pubmed/37381027
http://dx.doi.org/10.1186/s12964-023-01176-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304740/
https://www.ncbi.nlm.nih.gov/pubmed/37381027
http://dx.doi.org/10.1186/s12964-023-01176-3

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