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Downregulation of connexin 43-based gap junctions underlies propofol-induced excessive relaxation in hypertensive vascular smooth muscle cells

BACKGROUND: Postinduction hypotension caused by propofol remains a non-negligible problem for anesthesiologists, and is especially severe in chronic hypertensive patients with long-term vasoconstriction and decreased vascular elasticity. The functional change in gap junctions composed of Cx43 (Cx43-...

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Detalles Bibliográficos
Autores principales:	Zeng, Weiqi, Deng, Zhizhao, Gao, Yingxin, Sun, Guoliang, Li, Xianlong, Yuan, Dongdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304740/ https://www.ncbi.nlm.nih.gov/pubmed/37381027 http://dx.doi.org/10.1186/s12964-023-01176-3

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