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Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels

Over the last years, there has been a considerable expansion of genome-wide association studies (GWAS) for discovering biological pathways underlying pathological conditions or disease biomarkers. These GWAS are often limited to binary or quantitative traits analyzed through linear or logistic model...

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Detalles Bibliográficos
Autores principales: Munsch, Gaëlle, Proust, Carole, Labrouche-Colomer, Sylvie, Aïssi, Dylan, Boland, Anne, Morange, Pierre-Emmanuel, Roche, Anne, de Chaisemartin, Luc, Harroche, Annie, Olaso, Robert, Deleuze, Jean-François, James, Chloé, Emmerich, Joseph, Smadja, David M, Jacqmin-Gadda, Hélène, Trégouët, David-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304785/
https://www.ncbi.nlm.nih.gov/pubmed/37388819
http://dx.doi.org/10.1093/nargab/lqad062