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Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels
Over the last years, there has been a considerable expansion of genome-wide association studies (GWAS) for discovering biological pathways underlying pathological conditions or disease biomarkers. These GWAS are often limited to binary or quantitative traits analyzed through linear or logistic model...
Autores principales: | Munsch, Gaëlle, Proust, Carole, Labrouche-Colomer, Sylvie, Aïssi, Dylan, Boland, Anne, Morange, Pierre-Emmanuel, Roche, Anne, de Chaisemartin, Luc, Harroche, Annie, Olaso, Robert, Deleuze, Jean-François, James, Chloé, Emmerich, Joseph, Smadja, David M, Jacqmin-Gadda, Hélène, Trégouët, David-Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304785/ https://www.ncbi.nlm.nih.gov/pubmed/37388819 http://dx.doi.org/10.1093/nargab/lqad062 |
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