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Lipid Metabolism Reprogramming and Trastuzumab Resistance in Breast Cancer Cell Lines Overexpressing the ERBB2 Membrane Receptor

Trastuzumab (Tz), an antibody targeting ERBB2, has significantly improved the prognosis for breast cancer (BCa) patients with overexpression of the ERBB2 receptor. However, Tz resistance poses a challenge to patient outcomes. Numerous mechanisms have been suggested to contribute to Tz resistance, an...

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Detalles Bibliográficos
Autores principales: Cortese, Katia, Ponassi, Marco, Profumo, Aldo, Coronel Vargas, Gabriela, Iervasi, Erika, Gagliani, Maria Cristina, Bellese, Grazia, Tavella, Sara, Castagnola, Patrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304830/
https://www.ncbi.nlm.nih.gov/pubmed/37367744
http://dx.doi.org/10.3390/membranes13060540