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An online experimental medicine trial on the effect of 28-day simvastatin administration on emotional processing, reward learning, working memory and salivary cortisol in healthy volunteers at risk for depression: OxSTEP protocol

BACKGROUND: Evidence suggests inflammation may be a key mechanism by which psychosocial stress, including loneliness, predisposes to depression. Observational and clinical studies have suggested simvastatin, with its anti-inflammatory properties, may have a potential use in the treatment of depressi...

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Detalles Bibliográficos
Autores principales: Waters, Shona, De Giorgi, Riccardo, Quinton, Alice M. G., Gillespie, Amy L., Murphy, Susannah E., Cowen, Philip J., Harmer, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304861/
https://www.ncbi.nlm.nih.gov/pubmed/37313755
http://dx.doi.org/10.1192/bjo.2023.44