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Novel Tryptanthrin Derivatives with Selectivity as c–Jun N–Terminal Kinase (JNK) 3 Inhibitors

The c-Jun N-terminal kinase (JNK) family includes three proteins (JNK1-3) that regulate many physiological processes, including cell proliferation and differentiation, cell survival, and inflammation. Because of emerging data suggesting that JNK3 may play an important role in neurodegenerative disea...

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Detalles Bibliográficos
Autores principales: Schepetkin, Igor A., Karpenko, Oleksander S., Kovrizhina, Anastasia R., Kirpotina, Liliya N., Khlebnikov, Andrei I., Chekal, Stepan I., Radudik, Alevtyna V., Shybinska, Maryna O., Quinn, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304880/
https://www.ncbi.nlm.nih.gov/pubmed/37375361
http://dx.doi.org/10.3390/molecules28124806