Comprehensive Understanding of the Kinetic Behaviors of Main Protease from SARS-CoV-2 and SARS-CoV: New Data and Comparison to Published Parameters

The main protease (M(pro)) is a promising drug target for inhibiting the coronavirus due to its conserved properties and lack of homologous genes in humans. However, previous studies on M(pro)’s kinetic parameters have been confusing, hindering the selection of accurate inhibitors. Therefore, obtain...

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Detalles Bibliográficos
Autores principales: Li, Fangya, Fang, Tingting, Guo, Feng, Zhao, Zipeng, Zhang, Jianyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304930/
https://www.ncbi.nlm.nih.gov/pubmed/37375160
http://dx.doi.org/10.3390/molecules28124605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304930/
https://www.ncbi.nlm.nih.gov/pubmed/37375160
http://dx.doi.org/10.3390/molecules28124605

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