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Comprehensive Understanding of the Kinetic Behaviors of Main Protease from SARS-CoV-2 and SARS-CoV: New Data and Comparison to Published Parameters
The main protease (M(pro)) is a promising drug target for inhibiting the coronavirus due to its conserved properties and lack of homologous genes in humans. However, previous studies on M(pro)’s kinetic parameters have been confusing, hindering the selection of accurate inhibitors. Therefore, obtain...
Autores principales: | Li, Fangya, Fang, Tingting, Guo, Feng, Zhao, Zipeng, Zhang, Jianyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304930/ https://www.ncbi.nlm.nih.gov/pubmed/37375160 http://dx.doi.org/10.3390/molecules28124605 |
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