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Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers

This study aimed to formulate a pharmaceutical dosage form containing omeprazole (OMP) and curcumin (CURC) to treat experimental peptic ulcers. OMP and CURC were preliminarily complexed with hydroxypropyl-β-cyclodextrin for enhancing their solubilization. After that, the combined complex (CURC/OMP)...

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Detalles Bibliográficos
Autores principales: Heikal, Eman J., Kaoud, Rashad M., Gad, Shadeed, Mokhtar, Hatem I., Aldahish, Afaf A., Alzlaiq, Wafa Ali, Zaitone, Sawsan A., Moustafa, Yasser M., Hammady, Taha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305022/
https://www.ncbi.nlm.nih.gov/pubmed/37375745
http://dx.doi.org/10.3390/ph16060795