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Triphenylphosphonium (TPP)-Conjugated Quinolone Analogs Displayed Significantly Enhanced Fungicidal Activity Superior to Its Parent Molecule

Although 1-hydroxy-4-quinolone derivatives, such as 2-heptyl-4-hydroxyquinoline-N-oxide (HQNO), aurachin C, and floxacrine, have been reported as effective cytochrome bc(1) complex inhibitors, the bioactivity of these products is not ideal, presumably due to their low bioavailability in tissues, par...

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Detalles Bibliográficos
Autores principales: Wang, Jiayao, Liu, Xuelian, Yin, Fahong, Xu, Yanjun, Fu, Bin, Li, Jiaqi, Qin, Zhaohai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305039/
https://www.ncbi.nlm.nih.gov/pubmed/37367621
http://dx.doi.org/10.3390/jof9060685