Synthesis, Bioactivity and Molecular Docking of Nereistoxin Derivatives Containing Phosphonate

Novel nereistoxin derivatives containing phosphonate were synthesized and characterized via (31)P, (1)H and (13)C NMR and HRMS. The anticholinesterase activity of the synthesized compounds was evaluated on human acetylcholinesterase (AChE) using the in vitro Ellman method. Most of the compounds exhi...

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Detalles Bibliográficos
Autores principales: Yan, Qiaoli, Lu, Xiaogang, Zhang, Zixuan, Jin, Qian, Gao, Runli, Li, Liqin, Wang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305189/
https://www.ncbi.nlm.nih.gov/pubmed/37375402
http://dx.doi.org/10.3390/molecules28124846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305189/
https://www.ncbi.nlm.nih.gov/pubmed/37375402
http://dx.doi.org/10.3390/molecules28124846

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