Succinate dehydrogenase variants in paraganglioma: why are B subunit variants ‘bad’?

Mutations that predispose to familial pheochromocytoma and paraganglioma include inherited variants in the four genes (SDHA, SDHB, SDHC and SDHD) encoding subunits of succinate dehydrogenase (SDH), an enzyme of the mitochondrial tricarboxylic acid cycle and complex II of the electron transport chain...

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Detalles Bibliográficos
Autores principales: Gruber, Lucinda M, Hart, Steven N, Maher III, Louis James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305465/
https://www.ncbi.nlm.nih.gov/pubmed/37434649
http://dx.doi.org/10.1530/EO-22-0093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305465/
https://www.ncbi.nlm.nih.gov/pubmed/37434649
http://dx.doi.org/10.1530/EO-22-0093

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