Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus

Adenovirus has strong therapeutic potential as an oncolytic virus and gene therapy vector. However, injecting human species C serotype 5 adenovirus, HAdv-C5, into the bloodstream leads to numerous interactions with plasma proteins that affect viral tropism and biodistribution, and can lead to potent...

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Detalles Bibliográficos
Autores principales: Wagner, Nicole, Shayakhmetov, Dmitry M., Stewart, Phoebe L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305487/
https://www.ncbi.nlm.nih.gov/pubmed/37376642
http://dx.doi.org/10.3390/v15061343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305487/
https://www.ncbi.nlm.nih.gov/pubmed/37376642
http://dx.doi.org/10.3390/v15061343

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