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Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles

Despite their clinical success, Antibody-Drug Conjugates (ADCs) are still limited to the delivery of a handful of cytotoxic small-molecule payloads. Adaptation of this successful format to the delivery of alternative types of cytotoxic payloads is of high interest in the search for novel anticancer...

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Detalles Bibliográficos
Autores principales: Lehot, Victor, Neuberg, Patrick, Ripoll, Manon, Daubeuf, François, Erb, Stéphane, Dovgan, Igor, Ursuegui, Sylvain, Cianférani, Sarah, Kichler, Antoine, Chaubet, Guilhem, Wagner, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305667/
https://www.ncbi.nlm.nih.gov/pubmed/37376091
http://dx.doi.org/10.3390/pharmaceutics15061643