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Emerging Preclinical Applications of Humanized Mouse Models in the Discovery and Validation of Novel Immunotherapeutics and Their Mechanisms of Action for Improved Cancer Treatment

Cancer therapeutics have undergone immense research over the past decade. While chemotherapies remain the mainstay treatments for many cancers, the advent of new molecular techniques has opened doors for more targeted modalities towards cancer cells. Although immune checkpoint inhibitors (ICIs) have...

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Detalles Bibliográficos
Autores principales: Karnik, Isha, Her, Zhisheng, Neo, Shu Hui, Liu, Wai Nam, Chen, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305679/
https://www.ncbi.nlm.nih.gov/pubmed/37376049
http://dx.doi.org/10.3390/pharmaceutics15061600