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Lower Circulating Cytotoxic T-Cell Frequency and Higher Intragraft Granzyme-B Expression Are Associated with Inflammatory Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Recipients

Background and Objectives: Inflammatory interstitial fibrosis and tubular atrophy (i-IFTA) is an inflammation in the area of tubular atrophy and fibrosis. i-IFTA is poorly associated with graft outcome and associated with infiltration of inflammatory mononuclear cells. A cytotoxic T cell is a granzy...

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Detalles Bibliográficos
Autores principales: Yadav, Brijesh, Prasad, Narayan, Agrawal, Vinita, Agarwal, Vikas, Jain, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305683/
https://www.ncbi.nlm.nih.gov/pubmed/37374379
http://dx.doi.org/10.3390/medicina59061175