Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging

Age-dependent loss of skeletal muscle mass and function is a feature of sarcopenia, and increases the risk of many aging-related metabolic diseases. Here, we report phenotypic and single-nucleus transcriptomic analyses of non-human primate skeletal muscle aging. A higher transcriptional fluctuation...

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Detalles Bibliográficos
Autores principales: Jing, Ying, Zuo, Yuesheng, Yu, Yang, Sun, Liang, Yu, Zhengrong, Ma, Shuai, Zhao, Qian, Sun, Guoqiang, Hu, Huifang, Li, Jingyi, Huang, Daoyuan, Liu, Lixiao, Li, Jiaming, Xin, Zijuan, Huang, Haoyan, Belmonte, Juan Carlos Izpisua, Zhang, Weiqi, Wang, Si, Qu, Jing, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305740/
https://www.ncbi.nlm.nih.gov/pubmed/36921027
http://dx.doi.org/10.1093/procel/pwac061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305740/
https://www.ncbi.nlm.nih.gov/pubmed/36921027
http://dx.doi.org/10.1093/procel/pwac061

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