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A YAP/TAZ-CD54 axis is required for CXCR2(−)CD44(−) tumor-specific neutrophils to suppress gastric cancer

As an important part of tumor microenvironment, neutrophils are poorly understood due to their spatiotemporal heterogeneity in tumorigenesis. Here we defined, at single-cell resolution, CD44(−)CXCR2(−) neutrophils as tumor-specific neutrophils (tsNeus) in both mouse and human gastric cancer (GC). We...

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Detalles Bibliográficos
Autores principales: Nie, Pingping, Zhang, Weihong, Meng, Yan, Lin, Moubin, Guo, Fenghua, Zhang, Hui, Tong, Zhenzhu, Wang, Meng, Chen, Fan, An, Liwei, Tang, Yang, Han, Yi, Yu, Ruixian, Wang, Wenjia, Xu, Yuanzhi, Wei, Linxin, Zhou, Zhaocai, Jiao, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10305741/
https://www.ncbi.nlm.nih.gov/pubmed/36921037
http://dx.doi.org/10.1093/procel/pwac045