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Gene and pathway based burden analyses in familial lymphoid cancer cases: Rare variants in immune pathway genes
Genome-wide association studies have revealed common genetic variants with small effect sizes associated with diverse lymphoid cancers. Family studies have uncovered rare variants with high effect sizes. However, these variants explain only a portion of the heritability of these cancers. Some of the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306212/ https://www.ncbi.nlm.nih.gov/pubmed/37379307 http://dx.doi.org/10.1371/journal.pone.0287602 |