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Gene and pathway based burden analyses in familial lymphoid cancer cases: Rare variants in immune pathway genes

Genome-wide association studies have revealed common genetic variants with small effect sizes associated with diverse lymphoid cancers. Family studies have uncovered rare variants with high effect sizes. However, these variants explain only a portion of the heritability of these cancers. Some of the...

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Detalles Bibliográficos
Autores principales: Ralli, Sneha, Jones, Samantha J., Leach, Stephen, Lynch, Henry T., Brooks-Wilson, Angela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306212/
https://www.ncbi.nlm.nih.gov/pubmed/37379307
http://dx.doi.org/10.1371/journal.pone.0287602