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Lactobacillus rhamnosus GG and butyrate supplementation in rats with bone cancer reduces mechanical allodynia and increases expression of μ-opioid receptor in the spinal cord

INTRODUCTION: Chronic cancer pain is one of the most unbearable symptoms for the patients with advanced cancer. The treatment of cancer pain continues to possess a major challenge. Here, we report that adjusting gut microbiota via probiotics can reduce bone cancer pain (BCP) in rats. METHODS: The mo...

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Detalles Bibliográficos
Autores principales: Yuan, Wenxi, Xiao, Jie, Liao, Huabao, Xie, Zhiyuan, Zhao, Yiran, Li, Cheng, Zhou, Keying, Song, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306308/
https://www.ncbi.nlm.nih.gov/pubmed/37389091
http://dx.doi.org/10.3389/fnmol.2023.1207911