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Structural basis of NINJ1-mediated plasma membrane rupture in cell death

Eukaryotic cells can undergo different forms of programmed cell death, many of which culminate in plasma membrane rupture as the defining terminal event(1–7). Plasma membrane rupture was long thought to be driven by osmotic pressure, but it has recently been shown to be in many cases an active proce...

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Detalles Bibliográficos
Autores principales: Degen, Morris, Santos, José Carlos, Pluhackova, Kristyna, Cebrero, Gonzalo, Ramos, Saray, Jankevicius, Gytis, Hartenian, Ella, Guillerm, Undina, Mari, Stefania A., Kohl, Bastian, Müller, Daniel J., Schanda, Paul, Maier, Timm, Perez, Camilo, Sieben, Christian, Broz, Petr, Hiller, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307626/
https://www.ncbi.nlm.nih.gov/pubmed/37198476
http://dx.doi.org/10.1038/s41586-023-05991-z