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Mitotic clustering of pulverized chromosomes from micronuclei

Complex genome rearrangements can be generated by the catastrophic pulverization of missegregated chromosomes trapped within micronuclei through a process known as chromothripsis(1–5). As each chromosome contains a single centromere, it remains unclear how acentric fragments derived from shattered c...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Fen, Hu, Qing, Mazzagatti, Alice, Valle-Inclán, Jose Espejo, Maurais, Elizabeth G., Dahiya, Rashmi, Guyer, Alison, Sanders, Jacob T., Engel, Justin L., Nguyen, Giaochau, Bronder, Daniel, Bakhoum, Samuel F., Cortés-Ciriano, Isidro, Ly, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307639/
https://www.ncbi.nlm.nih.gov/pubmed/37165191
http://dx.doi.org/10.1038/s41586-023-05974-0