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Mitotic clustering of pulverized chromosomes from micronuclei
Complex genome rearrangements can be generated by the catastrophic pulverization of missegregated chromosomes trapped within micronuclei through a process known as chromothripsis(1–5). As each chromosome contains a single centromere, it remains unclear how acentric fragments derived from shattered c...
Autores principales: | Lin, Yu-Fen, Hu, Qing, Mazzagatti, Alice, Valle-Inclán, Jose Espejo, Maurais, Elizabeth G., Dahiya, Rashmi, Guyer, Alison, Sanders, Jacob T., Engel, Justin L., Nguyen, Giaochau, Bronder, Daniel, Bakhoum, Samuel F., Cortés-Ciriano, Isidro, Ly, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307639/ https://www.ncbi.nlm.nih.gov/pubmed/37165191 http://dx.doi.org/10.1038/s41586-023-05974-0 |
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