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Single-cell quantification of ribosome occupancy in early mouse development

Translation regulation is critical for early mammalian embryonic development(1). However, previous studies had been restricted to bulk measurements(2), precluding precise determination of translation regulation including allele-specific analyses. Here, to address this challenge, we developed a novel...

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Detalles Bibliográficos
Autores principales: Ozadam, Hakan, Tonn, Tori, Han, Crystal M., Segura, Alia, Hoskins, Ian, Rao, Shilpa, Ghatpande, Vighnesh, Tran, Duc, Catoe, David, Salit, Marc, Cenik, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307641/
https://www.ncbi.nlm.nih.gov/pubmed/37344592
http://dx.doi.org/10.1038/s41586-023-06228-9