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Human pancreatic ductal organoids with controlled polarity provide a novel ex vivo tool to study epithelial cell physiology
Epithelial ion and fluid secretion determine the physiological functions of a broad range of organs, such as the lung, liver, or pancreas. The molecular mechanism of pancreatic ion secretion is challenging to investigate due to the limited access to functional human ductal epithelia. Patient-derived...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307727/ https://www.ncbi.nlm.nih.gov/pubmed/37380797 http://dx.doi.org/10.1007/s00018-023-04836-2 |