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Human pancreatic ductal organoids with controlled polarity provide a novel ex vivo tool to study epithelial cell physiology

Epithelial ion and fluid secretion determine the physiological functions of a broad range of organs, such as the lung, liver, or pancreas. The molecular mechanism of pancreatic ion secretion is challenging to investigate due to the limited access to functional human ductal epithelia. Patient-derived...

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Detalles Bibliográficos
Autores principales: Varga, Árpád, Madácsy, Tamara, Görög, Marietta, Kiss, Aletta, Susánszki, Petra, Szabó, Viktória, Jójárt, Boldizsár, Dudás, Krisztina, Farkas, Gyula, Szederkényi, Edit, Lázár, György, Farkas, Attila, Ayaydin, Ferhan, Pallagi, Petra, Maléth, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307727/
https://www.ncbi.nlm.nih.gov/pubmed/37380797
http://dx.doi.org/10.1007/s00018-023-04836-2