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BMP-2 (and partially GDF-5) coating significantly accelerates and augments bone formation close to hydroxyapatite/tricalcium-phosphate/brushite implant cylinders for tibial bone defects in senile, osteopenic sheep

Bilateral defects (diameter 8 mm) in the medial tibial head of senile, osteopenic female sheep (n = 48; 9.63 ± 0.10 years; mean ± SEM) were treated with hydroxyapatite (HA)/beta-tricalcium phosphate (β-TCP)/dicalcium phosphate dihydrate (DCPD; brushite) cylinders coated with BMP-2 (25 or 250 microgr...

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Detalles Bibliográficos
Autores principales: Sachse, André, Hasenbein, Ines, Hortschansky, Peter, Schmuck, Klaus D., Maenz, Stefan, Illerhaus, Bernhard, Kuehmstedt, Peter, Ramm, Roland, Huber, René, Kunisch, Elke, Horbert, Victoria, Gunnella, Francesca, Roth, Andreas, Schubert, Harald, Kinne, Raimund W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307740/
https://www.ncbi.nlm.nih.gov/pubmed/37378714
http://dx.doi.org/10.1007/s10856-023-06734-2