Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red

Calcium homeostasis modulator 1 (CALHM1) is a voltage-dependent channel involved in neuromodulation and gustatory signaling. Despite recent progress in the structural biology of CALHM1, insights into functional regulation, pore architecture, and channel blockade remain limited. Here we present the c...

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Detalles Bibliográficos
Autores principales: Syrjänen, Johanna L., Epstein, Max, Gómez, Ricardo, Furukawa, Hiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307800/
https://www.ncbi.nlm.nih.gov/pubmed/37380652
http://dx.doi.org/10.1038/s41467-023-39388-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307800/
https://www.ncbi.nlm.nih.gov/pubmed/37380652
http://dx.doi.org/10.1038/s41467-023-39388-3

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