DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid

Mycobacterium tuberculosis is one of the global leading causes of death due to a single infectious agent. Pretomanid and delamanid are new antitubercular agents that have progressed through the drug discovery pipeline. These compounds are bicyclic nitroimidazoles that act as pro-drugs, requiring act...

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Detalles Bibliográficos
Autores principales: Abrahams, Katherine A., Batt, Sarah M., Gurcha, Sudagar S., Veerapen, Natacha, Bashiri, Ghader, Besra, Gurdyal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307805/
https://www.ncbi.nlm.nih.gov/pubmed/37380634
http://dx.doi.org/10.1038/s41467-023-39300-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307805/
https://www.ncbi.nlm.nih.gov/pubmed/37380634
http://dx.doi.org/10.1038/s41467-023-39300-z

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