In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer

BACKGROUND: Epigenomic dysregulation has been linked to solid tumour malignancies, including ovarian cancers. Profiling of re-programmed enhancer locations associated with disease has the potential to improve stratification and thus therapeutic choices. Ovarian cancers are subdivided into histologic...

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Detalles Bibliográficos
Autores principales: Quintela, Marcos, James, David W., Garcia, Jetzabel, Edwards, Kadie, Margarit, Lavinia, Das, Nagindra, Lutchman-Singh, Kerryn, Beynon, Amy L., Rioja, Inmaculada, Prinjha, Rab K., Harker, Nicola R., Gonzalez, Deyarina, Steven Conlan, R., Francis, Lewis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307814/
https://www.ncbi.nlm.nih.gov/pubmed/37120667
http://dx.doi.org/10.1038/s41416-023-02274-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307814/
https://www.ncbi.nlm.nih.gov/pubmed/37120667
http://dx.doi.org/10.1038/s41416-023-02274-2

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