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NK cell activity and methylated HOXA9 ctDNA as prognostic biomarkers in patients with non-small cell lung cancer treated with PD-1/PD-L1 inhibitors

BACKGROUND: PD-1/PD-L1 inhibitors have improved survival for patients with non-small cell lung cancer (NSCLC). We evaluated natural killer cell activity (NKA) and methylated HOXA9 circulating tumor DNA (ctDNA) as prognostic biomarkers in NSCLC patients treated with PD-1/PD-L1 inhibitors. METHODS: Pl...

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Detalles Bibliográficos
Autores principales: Wen, Sara Witting Christensen, Nederby, Line, Andersen, Rikke Fredslund, Hansen, Torben Schjødt, Nyhus, Christa Haugaard, Hilberg, Ole, Jakobsen, Anders, Hansen, Torben Frøstrup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307873/
https://www.ncbi.nlm.nih.gov/pubmed/37137997
http://dx.doi.org/10.1038/s41416-023-02285-z