Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis

Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action and the downstream mediators of curcumin’s tumor suppressive effects have remained largely unknown. Here we used a genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chunfeng, Rokavec, Matjaz, Huang, Zekai, Hermeking, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307888/
https://www.ncbi.nlm.nih.gov/pubmed/37210578
http://dx.doi.org/10.1038/s41418-023-01178-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307888/
https://www.ncbi.nlm.nih.gov/pubmed/37210578
http://dx.doi.org/10.1038/s41418-023-01178-1

Ejemplares similares