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UHRF1 inhibition epigenetically reprograms cancer stem cells to suppress the tumorigenic phenotype of hepatocellular carcinoma

Cancer stem cells (CSCs) contribute to tumor initiation, progression, and recurrence in many types of cancer, including hepatocellular carcinoma (HCC). Epigenetic reprogramming of CSCs has emerged as a promising strategy for inducing the transition from malignancy to benignity. Ubiquitin-like with P...

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Detalles Bibliográficos
Autores principales: Wang, Yanchen, Hu, Pengchao, Wang, Fenfen, Xi, Shaoyan, Wu, Shasha, Sun, Liangzhan, Du, Yuyang, Zheng, Jingyi, Yang, Hui, Tang, Mao, Gao, Han, Luo, Hao, Lv, Yue, Yan, Jingsong, Ou, Xijun, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307895/
https://www.ncbi.nlm.nih.gov/pubmed/37380646
http://dx.doi.org/10.1038/s41419-023-05895-w