Target Discovery Using Deep Learning-Based Molecular Docking and Predicted Protein Structures With AlphaFold for Novel Antipsychotics

OBJECTIVE: New drugs are needed to treat antipsychotic-resistant schizophrenia, especially those with clozapine-resistant schizophrenia. Atypical antipsychotics have predominantly 5-HT2A and dopaminergic antagonism, but also require investigation of other receptors. METHODS: In this study, the bindi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Yangsik, Kim, Seyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neuropsychiatric Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307917/
https://www.ncbi.nlm.nih.gov/pubmed/37248690
http://dx.doi.org/10.30773/pi.2022.0343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307917/
https://www.ncbi.nlm.nih.gov/pubmed/37248690
http://dx.doi.org/10.30773/pi.2022.0343

Ejemplares similares