Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphans with high‐to‐low MOR efficacy

Low‐efficacy mu‐opioid receptor (MOR) agonists represent promising therapeutics, but existing compounds (e.g., buprenorphine, nalbuphine) span a limited range of low MOR efficacies and have poor MOR selectivity. Accordingly, new and selective low‐efficacy MOR agonists are of interest. A novel set of...

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Detalles Bibliográficos
Autores principales: Santos, Edna J., Nassehi, Nima, Bow, Eric W., Chambers, Dana R., Gutman, Eugene S., Jacobson, Arthur E., Lutz, Joshua A., Marsh, Samuel A., Rice, Kenner C., Sulima, Agnieszka, Selley, Dana E., Negus, S. Stevens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307939/
https://www.ncbi.nlm.nih.gov/pubmed/37381112
http://dx.doi.org/10.1002/prp2.1111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307939/
https://www.ncbi.nlm.nih.gov/pubmed/37381112
http://dx.doi.org/10.1002/prp2.1111

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