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ALKBH5/YTHDF2‐mediated m6A modification of circAFF2 enhances radiosensitivity of colorectal cancer by inhibiting Cullin neddylation

BACKGROUND: Circular RNA (circRNA) and N6‐methyladenosine (m6A) play a critical role in tumour occurrence and development, including colorectal cancer (CRC). However, little is known about the interaction between circRNA and m6A in the radiosensitivity of CRC. Here, we investigated the role of a nov...

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Detalles Bibliográficos
Autores principales: Shao, Yingjie, Liu, Zhenhua, Song, Xing, Sun, Rui, Zhou, You, Zhang, Dachuan, Sun, Huihui, Huang, Junchao, Wu, Chenxi, Gu, Wendong, Zheng, Xiao, Jiang, Jingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10307995/
https://www.ncbi.nlm.nih.gov/pubmed/37381158
http://dx.doi.org/10.1002/ctm2.1318