Integration analysis of single-cell and spatial transcriptomics reveal the cellular heterogeneity landscape in glioblastoma and establish a polygenic risk model

BACKGROUND: Glioblastoma (GBM) is adults’ most common and fatally malignant brain tumor. The heterogeneity is the leading cause of treatment failure. However, the relationship between cellular heterogeneity, tumor microenvironment, and GBM progression is still elusive. METHODS: Integrated analysis o...

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Detalles Bibliográficos
Autores principales: Liu, Yaxuan, Wu, Zhenyu, Feng, Yueyuan, Gao, Jiawei, Wang, Bo, Lian, Changlin, Diao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308022/
https://www.ncbi.nlm.nih.gov/pubmed/37397378
http://dx.doi.org/10.3389/fonc.2023.1109037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308022/
https://www.ncbi.nlm.nih.gov/pubmed/37397378
http://dx.doi.org/10.3389/fonc.2023.1109037

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