RBL2 Regulates Cardiac Sensitivity to Anthracycline Chemotherapy

BACKGROUND: Anthracycline chemotherapies cause heart failure in a subset of cancer patients. We previously reported that the anthracycline doxorubicin (DOX) induces cardiotoxicity through the activation of cyclin-dependent kinase 2 (CDK2). OBJECTIVES: The aim of this study was to determine whether r...

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Detalles Bibliográficos
Autores principales: Xia, Peng, Chen, Jingrui, Sapkota, Yadav, Scott, Erika N., Liu, Yuening, Hudson, Melissa M., Rassekh, Shahrad R., Carleton, Bruce C., Ross, Colin J.D., Chow, Eric J., Cheng, Zhaokang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308060/
https://www.ncbi.nlm.nih.gov/pubmed/37397090
http://dx.doi.org/10.1016/j.jaccao.2022.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308060/
https://www.ncbi.nlm.nih.gov/pubmed/37397090
http://dx.doi.org/10.1016/j.jaccao.2022.10.017

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