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Neuropharmacology of human TERA2.cl.SP12 stem cell-derived neurons in ultra-long-term culture for antiseizure drug discovery

Modeling the complex and prolonged development of the mammalian central nervous system in vitro remains a profound challenge. Most studies of human stem cell derived neurons are conducted over days to weeks and may or may not include glia. Here we have utilized a single human pluripotent stem cell l...

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Detalles Bibliográficos
Autores principales: Salmanzadeh, Hamed, Poojari, Ankita, Rabiee, Atefeh, Zeitlin, Benjamin D., Halliwell, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308080/
https://www.ncbi.nlm.nih.gov/pubmed/37397467
http://dx.doi.org/10.3389/fnins.2023.1182720