Lack of interferon regulatory factor 3 leads to anxiety/depression-like behaviors through disrupting the balance of neuronal excitation and inhibition in mice

Disrupting the balance of neuronal excitation and inhibition (E/I) is an important pathogenic mechanism of anxiety and depression. Interferon regulatory factor 3 (IRF3) plays a key role in the innate immune response, and activation of IRF3 triggers the expression of type I interferons and downstream...

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Detalles Bibliográficos
Autores principales: Li, Junjie, Pang, Yayan, Du, Yehong, Xia, Lei, Chen, Mulan, Fan, Yepeng, Dong, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308133/
https://www.ncbi.nlm.nih.gov/pubmed/37396521
http://dx.doi.org/10.1016/j.gendis.2022.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308133/
https://www.ncbi.nlm.nih.gov/pubmed/37396521
http://dx.doi.org/10.1016/j.gendis.2022.05.003

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