The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype

Macrophages (Mφs) play a crucial role in the pathological progression of osteoarthritis (OA) by regulating inflammation and tissue repair. Decreasing pro-inflammatory M1-Mφs and increasing anti-inflammatory M2-Mφs can alleviate OA-related inflammation and promote cartilage repair. Apoptosis is a nat...

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Detalles Bibliográficos
Autores principales: Qin, Leilei, Yang, Jianye, Su, Xudong, Xilan li, Lei, Yiting, Dong, Lili, Chen, Hong, Chen, Cheng, Zhao, Chen, Zhang, Huan, Deng, Jun, Hu, Ning, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308169/
https://www.ncbi.nlm.nih.gov/pubmed/37396516
http://dx.doi.org/10.1016/j.gendis.2022.09.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308169/
https://www.ncbi.nlm.nih.gov/pubmed/37396516
http://dx.doi.org/10.1016/j.gendis.2022.09.010

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