Cargando…
The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype
Macrophages (Mφs) play a crucial role in the pathological progression of osteoarthritis (OA) by regulating inflammation and tissue repair. Decreasing pro-inflammatory M1-Mφs and increasing anti-inflammatory M2-Mφs can alleviate OA-related inflammation and promote cartilage repair. Apoptosis is a nat...
Autores principales: | Qin, Leilei, Yang, Jianye, Su, Xudong, Xilan li, Lei, Yiting, Dong, Lili, Chen, Hong, Chen, Cheng, Zhao, Chen, Zhang, Huan, Deng, Jun, Hu, Ning, Huang, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308169/ https://www.ncbi.nlm.nih.gov/pubmed/37396516 http://dx.doi.org/10.1016/j.gendis.2022.09.010 |
Ejemplares similares
-
Small extracellular vesicles from Ptpn1-deficient macrophages alleviate intestinal inflammation by reprogramming macrophage polarization via lactadherin enrichment
por: Han, Dandan, et al.
Publicado: (2022) -
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction
por: Dai, Zhanqiu, et al.
Publicado: (2022) -
Macrophage Migration Inhibitory Factor on Apoptotic Extracellular Vesicles Regulates Compensatory Proliferation
por: Essien, Safia A., et al.
Publicado: (2023) -
Extracellular Vesicles from Apoptotic Cells Promote TGFβ Production in Macrophages and Suppress Experimental Colitis
por: Chen, Hua, et al.
Publicado: (2019) -
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination
por: Yuan, Gongsheng, et al.
Publicado: (2021)