scHi-CSim: a flexible simulator that generates high-fidelity single-cell Hi-C data for benchmarking

Single-cell Hi-C technology provides an unprecedented opportunity to reveal chromatin structure in individual cells. However, high sequencing cost impedes the generation of biological Hi-C data with high sequencing depths and multiple replicates for downstream analysis. Here, we developed a single-c...

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Detalles Bibliográficos
Autores principales: Fan, Shichen, Dang, Dachang, Ye, Yusen, Zhang, Shao-Wu, Gao, Lin, Zhang, Shihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308180/
https://www.ncbi.nlm.nih.gov/pubmed/36708167
http://dx.doi.org/10.1093/jmcb/mjad003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308180/
https://www.ncbi.nlm.nih.gov/pubmed/36708167
http://dx.doi.org/10.1093/jmcb/mjad003

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