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scHi-CSim: a flexible simulator that generates high-fidelity single-cell Hi-C data for benchmarking
Single-cell Hi-C technology provides an unprecedented opportunity to reveal chromatin structure in individual cells. However, high sequencing cost impedes the generation of biological Hi-C data with high sequencing depths and multiple replicates for downstream analysis. Here, we developed a single-c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308180/ https://www.ncbi.nlm.nih.gov/pubmed/36708167 http://dx.doi.org/10.1093/jmcb/mjad003 |