Triplet-primed PCR and Melting Curve Analysis for Rapid Molecular Screening of Spinocerebellar Ataxia Types 1, 2, and 3

There are more than 40 types of spinocerebellar ataxia (SCA), most of which are caused by abnormal expansion of short tandem repeats at various gene loci. These phenotypically similar disorders require molecular testing at multiple loci by fluorescent PCR and capillary electrophoresis to identify th...

Descripción completa

Detalles Bibliográficos
Autores principales: Lian, Mulias, Zhao, Mingjue, Phang, Gui-Ping, Rajan-Babu, Indhu-Shree, Chong, Samuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308190/
https://www.ncbi.nlm.nih.gov/pubmed/37397792
http://dx.doi.org/10.21769/BioProtoc.4704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10308190/
https://www.ncbi.nlm.nih.gov/pubmed/37397792
http://dx.doi.org/10.21769/BioProtoc.4704

Ejemplares similares